Using Dedicated and Opportunistic Networks in Synergy for a Cost-effective Distributed Stream Processing Platform

This paper presents a case for exploiting the synergy of dedicated and opportunistic network resources in a distributed hosting platform for data stream processing applications. Our previous studies have demonstrated the benefits of combining dedicated reliable resources with opportunistic resources in case of high-throughput computing applications, where timely allocation of the processing units is the primary concern. Since distributed stream processing applications demand large volume of data transmission between the processing sites at a consistent rate, adequate control over the network resources is important here to assure a steady flow of processing. In this paper, we propose a system model for the hybrid hosting platform where stream processing servers installed at distributed sites are interconnected with a combination of dedicated links and public Internet. Decentralized algorithms have been developed for allocation of the two classes of network resources among the competing tasks with an objective towards higher task throughput and better utilization of expensive dedicated resources. Results from extensive simulation study show that with proper management, systems exploiting the synergy of dedicated and opportunistic resources yield considerably higher task throughput and thus, higher return on investment over the systems solely using expensive dedicated resources.Comment: 9 page

CliqueStream: an efficient and fault-resilient live streaming network on a clustered peer-to-peer overlay

Several overlay-based live multimedia streaming platforms have been proposed in the recent peer-to-peer streaming literature. In most of the cases, the overlay neighbors are chosen randomly for robustness of the overlay. However, this causes nodes that are distant in terms of proximity in the underlying physical network to become neighbors, and thus data travels unnecessary distances before reaching the destination. For efficiency of bulk data transmission like multimedia streaming, the overlay neighborhood should resemble the proximity in the underlying network. In this paper, we exploit the proximity and redundancy properties of a recently proposed clique-based clustered overlay network, named eQuus, to build efficient as well as robust overlays for multimedia stream dissemination. To combine the efficiency of content pushing over tree structured overlays and the robustness of data-driven mesh overlays, higher capacity stable nodes are organized in tree structure to carry the long haul traffic and less stable nodes with intermittent presence are organized in localized meshes. The overlay construction and fault-recovery procedures are explained in details. Simulation study demonstrates the good locality properties of the platform. The outage time and control overhead induced by the failure recovery mechanism are minimal as demonstrated by the analysis.Comment: 10 page

Integrated cage-cum-pond culture systems with high valued climbing perch (Anabas testudineus) in cages and low-valued carps in open ponds

An on-farm trial was conducted over 150 days to determine appropriate stocking ratio, growth and production of climbing perch (Anabas testudineus) in cages and carps in open water of ponds in eighteen farmers' ponds from Haluaghat Upazila at Mymensingh district of Bangladesh. One or two 1 m super(3) cage was suspended in each of 12 earthen ponds and other 6 ponds served as control without cages. Climbing perch of 2-3 g in size were stocked in cages while fingerlings of silver carp (Hypophthalmicthys molitrix), catla (Catla catla), rohu (Labeo rohita), mirgal (Cirhinus cirrhosus), rajputi (Puntius sarana) and common carp (Cyprinus carpio) were stocked at 1 fish/m super(2) with a species ratio of 5:4:4:4:2:1 in open water of all ponds to give cage to open-pond fish ratios of 1:1 (T sub(1:1)) and 2:1 (T sub(2:1)) and 0:1 (T sub(0:1)) as three treatments with six replicates each. Survival of climbing perch was higher in T sub(1:1) (61.67%) than that of T sub(2:1) (29.5%) and was significantly different (p>0.05) between the treatments. Stocking of small size climbing perch fry increased the mortality rate in cages. The net yields of Thai koi were 0.13±0.01 (t/ha) and 0.10±0.01 (t/ha) in treatments T sub(1:1) and T sub(2:1), respectively and both were significantly different (p>0.05). Survival of-open-pond carps was high, ranging from 50 to 91.67% with significantly lower in T sub(0:1) than that of T sub(1:1) and T sub(2:1) treatment. Net and gross yield of each carp species were significantly higher in the T sub(1:1) and T sub(2:1) treatment than that in T sub(0:1) treatment. Net revenues were positive but low in all treatments. Therefore, bigger size climbing perch with lower stocking ratio (T sub(1:1)) is suitable for integrated cage-pond culture of climbing perch and carps. However, more on-farm trials in different ecosystem with scientific interventions are necessary to develop the technology for further dissemination among the rural farmers

Bangladesh’s 2023 Dengue outbreak – age/gender-related disparity in morbidity and mortality and geographic variability of epidemic burdens

Bangladesh is currently grappling to control its most devastating dengue fever outbreak recorded since the dengue virus (DENV) reappeared in the country in 2000 [1, 2, 3]. Although dengue is endemic in Bangladesh, the current dengue surge is unusual in terms of case burden and mortality, seasonality, and the early sharp increase [[1]]. Between 1 January and 25 August 2023, a total of 110,224 DENV infections including 528 deaths (case fatality ratio [CFR]: 0.48%) were recorded [[2]]. The reported number of dengue cases and deaths this year so far is already the highest ever recorded in the country, while the numbers are continuing to rise [1, 2, 3]. The Bangladesh Ministry of Health and Family Welfare's Management Information System (MIS) provides daily reports on cases, deaths, and the district-wise distribution of DENV infections [[2]]. Analyses of data from inpatient records and geographic coordinates of residence locations between 1 January and 17 August 2023 highlight four important findings that require further epidemic investigation: First, approximately half of the cases (n=52,656) were recorded in the capital city Dhaka, and 86% of them were located within a 2-km radius of hospitals, raising concern about the high density of DENV patients in the proximity of the hospitals (Fig. 1). Second, although 62% of the cases are males, 58% of the deaths are females indicating a higher risk of mortality among females. Third, we identified a possible age-specific disparity in morbidity and mortality indicating more severe infections in the older age group. People ≥30 years old accounted for 38% of cases and 64% of deaths in 2023. Fourth, out of 528 deaths, 391 (74%) were recorded among the patients hospitalized in the capital city, Dhaka (Fig. 2)

DNA damage in obesity: Initiator, promoter and predictor of cancer

Epidemiological evidence linking obesity with increased risk of cancer is steadily growing, although the causative aspects underpinning this association are only partially understood. Obesity leads to a physiological imbalance in the regulation of adipose tissue and its normal functioning, resulting in hyperglycaemia, dyslipidaemia and inflammation. These states promote the generation of oxidative stress, which is exacerbated in obesity by a decline in anti-oxidant defence systems. Oxidative stress can have a marked impact on DNA, producing mutagenic lesions that could prove carcinogenic. Here we review the current evidence for genomic instability, sustained DNA damage and accelerated genome ageing in obesity. We explore the notion of genotoxicity, ensuing from systemic oxidative stress, as a key oncogenic factor in obesity. Finally, we advocate for early, pre-malignant assessment of genome integrity and stability to inform surveillance strategies and interventions